alpha-Crystallin from bovine eye lens, lyophilized powder

Application

α-Crystallin is a lens protein that contains two homologous subunits: αA- and αB-crystallins. α-Crystallin displays chaperone-like activity and plays an important role in maintaining lens transparency. It has been noted that in diabetic conditions of rats there is a decline in the chaperone activity of α-Crystallin. Research has shown that a dietary antioxidant, curcumin, can prevent this loss of chaperone activity.

Biochem/physiol Actions

α-Crystallin is a small heat-shock protein that has chaperone-like activity, preventing protein aggregation in vitro. Point mutations in α-crystallin genes are believed to be responsible for hereditary cataract development.

Packaging

5 mg in glass bottle

25 mg in poly bottle

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Code Description Quality Level Manufacturer Technique(s) Storage Temp. Form Assay Price Quantity
3589886 alpha-Crystallin from bovine eye lens, lyophilized powder 200 SIGMA-ALDRICH cell culture - mammalian: suitable −20°C lyophilized powder ≥70% (biuret)
£721.87 (exc VAT) per 25MG
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3589887 alpha-Crystallin from bovine eye lens, lyophilized powder 200 SIGMA-ALDRICH cell culture - mammalian: suitable −20°C lyophilized powder ≥70% (biuret)
£191.01 (exc VAT) per 5MG
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