alpha-Casein from bovine milk, alphas-casein basis (electrophoresis), >=70% alphas-casein basis (ele

Application

α-Casein from bovine milk is an Immunoglobulin E (IgE)-binding epitope belonging to the Casein phosphoprotein family. It has been used in studies of children with insulin-dependent diabetes mellitus (IDDM), due to the strong cross-reactivity of α-casein antibodies with insulin. Studies of children displaying (IDDM) show higher levels of α-casein antibodies than control siblings, which may serve as a risk marker for IDDM.

Biochem/physiol Actions

α-Casein can be an immunogen in young children, and anti-a-casein antibodies have strong cross-reactivity with insulin. This effect can explain the uncommon insulin autoimmunity, but it does not appear to progress to Type I diabetes.

Packaging

1, 5 g in poly bottle

250 mg in poly bottle

Preparation Note

Chromatographically purified

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Code Description Quality Level Manufacturer Technique(s) Storage Temp. Form Assay Price Quantity
3589951 alpha-Casein from bovine milk, alphas-casein basis (electrophoresis), >=70% alphas-casein basis (ele 200 SIGMA-ALDRICH mass spectrometry (MS): suitable −20°C lyophilized powder ≥70% αs-casein basis (electrophoresis)
£305.04 (exc VAT) per 1G
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3589952 alpha-Casein from bovine milk, alphas-casein basis (electrophoresis), >=70% alphas-casein basis (ele 200 SIGMA-ALDRICH mass spectrometry (MS): suitable −20°C lyophilized powder ≥70% αs-casein basis (electrophoresis)
£104.19 (exc VAT) per 250MG
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3589953 alpha-Casein from bovine milk, alphas-casein basis (electrophoresis), >=70% alphas-casein basis (ele 200 SIGMA-ALDRICH mass spectrometry (MS): suitable −20°C lyophilized powder ≥70% αs-casein basis (electrophoresis)
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