S-Nitroso-N-acetyl-DL-penicillamine, >=97%, powder
Application
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) has been used:as a positive control in nitrite generation assay.to block the activity of endogenous transglutaminase (TG2).in proliferation assays to generate nitric oxide (NO) in cell cultures.
Biochem/physiol Actions
NO donor; vasodilator, smooth muscle relaxant, lymphocyte activator. Activates soluble guanylyl cyclase.
SNAP, a nitrosothiol derivative, releases nitric oxide (NO.) under physiological conditions thus making it a useful tool for studying pharmacological and physiological actions of NO. Because of its NO releasing properties SNAP is a potent vasodilator in vitro and in vivo and is less prone to produce pharmacological tolerance.
Packaging
50 mg in glass bottle
25 mg in poly bottle
| Colour | faint green to very dark green |
|---|---|
| Quality Level | 300 |
| InChI key | ZIIQCSMRQKCOCT-UHFFFAOYSA-N |
| InChI | 1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12) |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | H2O: ≥2 mg/mL, DMSO: ≥20 mg/mL, clear (faint green to very dark green) |
| Form | powder |
| Assay | ≥97% |
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