Pentagastrin, >=95% (HPLC), powder
Amino Acid Sequence
Boc-Bal-Trp-Met-Asp-Phe-NH2
Application
Pentagastrin has been used to bidirectionally modulate lateral nucleus of the amygdala (LA) activity.
Biochem/physiol Actions
CCKB agonist that stimulates gastric acid secretion; anxiogenic.Pentagastrin is an agonist of the cholecystokinin-2 (CCK2) receptor. It helps to increase the excitability of neurons in the basolateral amygdala through the activation of a non-specific cation channel.
General description
CCK2R (cholecystokinin 2 receptor) is also referred as CCKBR. It is a G-protein coupled receptor, that is expressed in the central nervous system and throughout the gastrointestinal tract. CCK2R is located on human 11p15.
Packaging
25, 100 mg in serum bottle
| Quality Level | 200 |
|---|---|
| InChI key | NEYNJQRKHLUJRU-UHFFFAOYSA-N |
| InChI | 1S/C37H49N7O9S/c1-37(2,3)53-36(52)39-16-14-30(45)41-28(19-23-21-40-25-13-9-8-12-24(23)25)34(50)42-26(15-17-54-4)33(49)44-29(20-31(46)47)35(51)43-27(32(38)48)18 |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Form | powder |
| Assay | ≥95% (HPLC) |
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