Ovalbumin (323-339) (chicken, Japanese quail),

Stock Code: 3591900
Manufacturer Part No: O1641-1MG
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£276.86 (exc VAT) per 1MG
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Amino Acid Sequence

H-Ile-Ser-Gln-Ala-Val-His-Ala-Ala-His-Ala-Glu-Ile-Asn-Glu-Ala-Gly-Arg-OH

Application

Ovalbumin (323-339) (chicken, Japanese quail) has been used to induce allergic asthma in mice.

Biochem/physiol Actions

With the help of two functionally distinct registers ovalbumin (323-339) peptide can bind to histocompatibility complex class II I-A(d) protein.

Ovalbumin (OVA) peptide 323-339 mediates 25–35% of T-cell response to intact OVA in isolated BALB/c mouse. OVA 323-339 has been widely used to determine the characteristics of class II major histocompatibility complex (MHC)-peptide binding and T-cell activation.

General description

Ovalbumin (323-339) is an egg white protein surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition to this, it also contains CD4+ T cell epitopes.

The peptide is a major MHC class II-restricted T-cell epitope of Ovalbumin which is used for studies of immunological allergic responses such as asthma, food allergy and more..

Other Notes

Lyophilized from 0.1% TFA in H2O

Physical form

Lyophilized from 0.1% aqueous TFA

Colourwhite
Quality Level200
ManufacturerSIGMA-ALDRICH
Compositionpeptide content, 65-100%
Storage Temp.−20°C
Solubilitywater, double-distilled: soluble
Formlyophilized powder
Assay97-100% (HPLC)

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