O-Phospho-L-serine,
Application
O-Phospho-L-serine has been used:for the expression, purification and phosphorylation of proteinto study its chemical shift to spectroscopically determine its pKa values using Raman spectroscopy
Biochem/physiol Actions
O-Phospho-L-serine (L-SOP) is a molecule which resembles phosphatidylserine head group and it mediates partial inhibition of microglial phagocytosis of apoptotic cells. In zebrafish, L-SOP inhibits Müller glia proliferation and blocks cone cell regeneration in the light-damaged retina. In vivo, L-SOP acts as a substrate for CysM, a cysteine synthase from Mycobacterium tuberculosis.
Group III metabotropic glutamate receptor agonist (mGluR4, mGluR7, and mGluR8).
Packaging
10 mg in autosample vial
| Quality Level | 200 |
|---|---|
| mp | 190 °C (lit.) |
| InChI key | BZQFBWGGLXLEPQ-REOHCLBHSA-N |
| InChI | 1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1 |
| Manufacturer | SIGMA-ALDRICH |
| Form | powder |
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