Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse, lyophilized powder

Stock Code: 3591773
Manufacturer Part No: M4199-500UG
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Amino Acid Sequence

Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly

Biochem/physiol Actions

The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.

Other Notes

Lyophilized from 0.1% TFA in H2O

Physical form

Lyophilized from 0.1% aqueous TFA.

Colourwhite
Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Solubilitydeionized water: soluble
Formlyophilized powder
Assay≥97% (HPLC)

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