L-2-Aminoadipic acid, >=98% (TLC)

Stock Code: 3589619
Manufacturer Part No: A7275-100MG
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£88.45 (exc VAT) per 100MG
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Application

L-2-Aminoadipic acid has been used as a gliotoxin specific for astrocytes in rat. It has also been as an internal standard in the amino acid analysis from fermented food sample.

Biochem/physiol Actions

L-2-Aminoadipic acid inhibits glutamine synthetase and ?-glutamylcysteine synthetase. It modulates glucose metabolism and is present in higher levels in diabetic patients. L-2-Aminoadipic acid plays a key role in suppressing autophagy in C2C12 myotubes.

General description

L-2-Aminoadipic acid/?-aminoadipate is a gliotoxin and is a structural analog of glutamine. It is generated by the catabolism of lysine saccharopine (SAC)/pipecolic acid (PIP) pathways.

Packaging

1, 5 g in poly bottle

100, 250 mg in poly bottle

Quality Level200
mp203-205 °C (dec.) (lit.)
InChI keyOYIFNHCXNCRBQI-BYPYZUCNSA-N
InChI1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m0/s1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (TLC)

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