Heregulin-beta1 (EGF Domain) human, >=98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, ly

Stock Code: 3573400
Manufacturer Part No: H7660-10UG
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Analysis Note

The biological activity is measured by its ability to stimulate the proliferation of human MCF-7 cells grown under serum-free conditions.

Biochem/physiol Actions

Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways.

Colourwhite
Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Impuritiesendotoxin, tested
Formlyophilized powder
Assay≥98% (SDS-PAGE)

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