Heparin sodium salt from porcine intestinal mucosa, endotoxin, free

Stock Code: 3589241
Manufacturer Part No: 2106-15VL
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Application

Heparin sodium salt from porcine intestinal mucosa has been used as a M199 medium supplement used for maintaining human umbilical vein endothelial cells.

Biochem/physiol Actions

Heparin sodium salt is the salt form of heparinic acid and is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is an anticoagulant that produces its major anticoagulant effect by activating antithrombin. Heparin binds to antithrombin III, a naturally occurring plasma protease inhibitor and accelerates significantly the rate at which antithrombin III (AT-III) inhibits coagulation proteases (factor Xa and thrombin). Additionally, it also facilitates the stabilization and regulation of tryptase as an enzymatically active tetramer.

Caution

Not for injection.

Legal Information

E-Toxate is a trademark of Sigma-Aldrich Co. LLC

Quality Level200
ManufacturerSIGMA-ALDRICH
Compatibilityfor use with E-Toxate™
Impuritiesendotoxin, free
Solubilitychloroform: insoluble, acetone: insoluble, alcohol: insoluble, benzene: insoluble, water: soluble 50 g/L, diethyl ether: insoluble
Formpowder

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