Hemoglobin A0, Ferrous Stabilized human, lyophilized powder

Stock Code: 3591398
Manufacturer Part No: H0267-25MG

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Descriptions

Application

Hemoglobin A₀ was used to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype. It was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay.

Hemoglobin A0, ferrous stabilized human has been used:as the non-fluorescent absorber in the preparation of tissue-mimicking phantomsto see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotypeto study the interference of hemoglobin (Hb) A0, HbA2, and HbS in the assay of HbF

Biochem/physiol Actions

Variation in the haemoglobin (Hb) encoding genes results in haemoglobinopathies such as thalassaemia and atypical structural variants like Hb Lepore and HbE.

General description

Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.

Packaging

Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946).

Reconstitution

When reconstituted with buffer, gives >85% ferrous hemoglobin.

Specifications

Quality Level	200
Manufacturer	SIGMA-ALDRICH
Storage Temp.	−20°C
Suitability	suitable for electrophoresis and chromatography standard (has not been tested for functional equivalence against native preparations (unlyophilized ferrous hem
Solubility	H2O: soluble 20 mg/mL
Form	lyophilized powder
Assay	97-100% (agarose gel electrophoresis)