Glycine, (based on anhydrous substance), meets analytical specification of Ph. Eur., BP, USP, 99-101

Stock Code: 3589205
Manufacturer Part No: 15527-2.5KG-R
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Application

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes. It was used for biochemical and tolerance tests.

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS. During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria. It also increases the in vitro development of porcine blastocysts when used along with glucose.

Colourwhite
Quality Level200
mp240 °C (dec.) (lit.)
pH5.9-6.4 (20 °C, 5%)
InChI keyDHMQDGOQFOQNFH-UHFFFAOYSA-N
InChI1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
ManufacturerSIGMA-ALDRICH
Suitabilitycomplies for reaction against H2SO4; in accordance for identity (IR); complies for appearance of solution
Impuritieshydrolyzable substances, complies; ≤0.001% heavy metals (as Pb); ≤1.0% ninhydrin-positive substances; organic volatile impurities, complies (GC); residua
SolubilityH2O: soluble 25 gm in 100 ml at 25 degrees c; diethyl ether: very slightly soluble; pyridine: soluble 164 parts; H2O: soluble 39.1 gm in
Formcrystalline powder
Assay99-101% (based on anhydrous substance)
Loss≤0.2% loss on drying, 105 °C, 2 h

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