GLP-2 1-33 rat / Preproglucagon 126-158 / Glp 2 rat, >=95% (HPLC)

Stock Code: 3592429
Manufacturer Part No: SCP0155-500UG
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Amino Acid Sequence


His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Thr-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp


Biochem/physiol Actions


Glucagon-like peptide 2 (GLP-2) plays a key role in the stimulation of intestinal epithelial proliferation. It possesses intestinotrophic endocrine/paracrine actions. GLP-2 is essentially a nutrition absorption regulator and an intestinal-specific trophic factor. It exhibits anti-inflammatory effects.


Glycogen-like peptide-2 (GLP-2) is involved in a range of processes in vivo including intestinal growth, reduction in bone breakage appetite and neuroprotection. GLP-2 human and GLP-2 rat may be used to study these and other processes.


General description


Glucagon-like peptide 2 (GLP-2), an intestinal specific trophic hormone, is a gastrointestinal peptide with 33% sequence homology to glucagon. L-cells on the mucosa of the small intestine and colon release this enteroendocrine hormone.

ManufacturerSIGMA-ALDRICH
CompositionPeptide Content, ≥75%
Storage Temp.−20°C
Formlyophilized
Assay≥95% (HPLC)

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