GLP-1 (Preproglucagon 72-107 amide) (GLP-1 human), >=98% (HPLC)

Stock Code: 3592426
Manufacturer Part No: SCP0153-1MG
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£675.54 (exc VAT) per 1MG
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Amino Acid Sequence


His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2


Application


Glycogen-like peptide-1 (GLP-1) is an amino acid peptide derived from proglucogon. GLP-1 is involved in the regulation of the glycemic index via its affect on glucagon and insulin levels. GLP-1 may be used to study its interaction with its receptor, the GLP-1 receptor.


GLP-1 (Preproglucagon 72-107 amide) (GLP-1 human) has been used to study its effect on vascular endothelial growth factor-A (VEGFA)-mediated endothelium-dependent signaling and vasodilation.


Biochem/physiol Actions


Glycogen-like peptide-1 (GLP-1) is an insulinotropic hormone, which takes part in increasing insulin secretion and insulin sensitivity. It also inhibits the secretion of glycogen and reduces fasting glucose levels.

ManufacturerSIGMA-ALDRICH
CompositionPeptide Content, ≥75%
Storage Temp.−20°C
Formlyophilized
Assay≥95% (HPLC)

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