gamma-Globulins from bovine blood, >=99% (agarose gel electrophoresis)

Stock Code: 3591327
Manufacturer Part No: G5009-10G
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Application

Bovine ?-globulins were used to study the constituents and pH changes in protein rich hyaluronan solution which affect the biological properties of artificial articular joints. It is also used to determine immunoglobulin G in bovine colostrum and milk using direct biosensor SPR-immunoassay.

Bovine γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance.

Biochem/physiol Actions

The ?-G globulins of bovine serum are categorized by anion exchange chromatography, immunoelectrophoresis, zone electrophoresis, ultracentrifugation, and analysis of the products of papain digestion. They have properties similar to analogous components of human serum. This was determined by the methods such as: gel filtration, immunoelectrophoresis, anion exchange chromatography, ultracentrifugation, and reduction with mercaptoethanol. Fast and slow ?-G globulins were classified on the basis of differences in electrophoretic migration rates, chromatographic elution positions, and biological activities (complement fixation). Bovine ?-A was conditionally found in immunoelectrophoretic analyses of serum and chromatographic fractions.

General description

Plasma protein fraction rich in antibodies

Packaging

1, 5, 10, 25, 100 g in poly bottle

Preparation Note

Prepared from Cohn Fraction II, III

Quality Level300
ManufacturerSIGMA-ALDRICH
Technique(s)enzyme immunoassay: suitable
CompositionNaCl, ≤4%
Storage Temp.−20°C
Solubility0.9% NaCl: soluble 25 mg/mL
Formpowder
Assay≥99% (agarose gel electrophoresis)

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