Galanthamine hydrobromide from Lycoris sp., >=94% (TLC)
Application
Galanthamine hydrobromide from Lycoris sp. has been used-as an AChE (acetylcholinesterase) inhibitor and positive control in acetylcholinesterase assay performed to determine the activity of AChE as a positive control in the screening of AChE inhibitorsas a positive control in AChE inhibitory assay performed to determine the AChE-inhibitory activities of pyrithione and related sulfur-containing pyridine N-oxides
Biochem/physiol Actions
Cholinesterase inhibitor; reverses scopolamine-induced amnesia; antimyasthenic.
General description
Galanthamine hydrobromide is a derivative of galanthamine, which is an anticholinestrase alkaloid derived from genus Lycoris (Amaryllidaceae) or snowdrop. This compound is used for the treatment of Alzheimer’;s disease (AD).
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
| Quality Level | 100 |
|---|---|
| mp | 270 °C |
| InChI key | QORVDGQLPPAFRS-XPSHAMGMSA-N |
| InChI | 1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1 |
| Manufacturer | SIGMA-ALDRICH |
| Form | powder |
| Assay | ≥94% (HPLC) |
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