Dynorphin A porcine, >=95% (HPLC)
Amino Acid Sequence
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln
Application
Dynorphin A has been used in immunohistochemistry.
Biochem/physiol Actions
Dynorphin A porcine is an opioid peptide. It is an endogenous ?-agonist that is resistant to enzymatic degradation. Dynorphin A has the ability to decrease calcium current by selectively decreasing the large inactivating (N) calcium current. It can decrease the calcium-dependent action potential duration of DRG (dorsal root ganglion) and myenteric neurons.
| Quality Level | 200 |
|---|---|
| InChI key | JMNJYGMAUMANNW-FIXZTSJVSA-N |
| InChI | 1S/C99H155N31O23/c1-7-55(6)81(129-86(142)66(28-18-40-112-98(107)108)118-83(139)65(27-17-39-111-97(105)106)120-88(144)70(44-54(4)5)125-89(145)71(46-56-21-9-8-10 |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Form | powder |
| Assay | ≥95% (HPLC) |
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