DL-2-Amino-5-phosphonopentanoic acid, solid
Application
DL-2-Amino-5-phosphonopentanoic acid has been used:in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapsesused in growth medium for inhibition of electrical activity in the neuronal networkused to isolate N-methyl-D-aspartate receptors (NMDAR) or ?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)-mediated currents were isolated using this productused in double distilled water to compare its NMDA antagonistic action with that of prion protein (PrPC)
Biochem/physiol Actions
Anticonvulsant; potent and selective NMDA receptor antagonist.
Caution
Hygroscopic
Packaging
10, 25, 50, 100 mg in glass bottle
| Colour | white |
|---|---|
| InChI key | VOROEQBFPPIACJ-UHFFFAOYSA-N |
| InChI | 1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11) |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | H2O: 5.6 mg/mL, organic solvents: insoluble, 0.1 M NaOH: 4 mg/mL |
| Form | solid |
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