Daunorubicin hydrochloride, meets USP testing specifications

Stock Code: 3591079
Manufacturer Part No: D8809-10MG
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£565.00 (exc VAT) per 10MG
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Biochem/physiol Actions

Potent anticancer agent. Inhibits DNA and RNA synthesis as sequence specific ds-DNA intercalating agent.

Naturally fluorescent anthracycline antibiotic, anticancer drug. Substrate for Pgp, MRP-1 and BCRP. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes. Daunorubicin is sequestered into lysosomes according to a pH partitioning type mechanism. Strong inhibitor of DNA and RNA synthesis.

Packaging

1, 10 mg in glass bottle

50 mg in poly bottle

Quality Level200
InChI keyGUGHGUXZJWAIAS-QQYBVWGSSA-N
InChI1S/C27H29NO10.ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33;/h4-6,10,14,16-17,22
ManufacturerSIGMA-ALDRICH
Agencymeets USP testing specifications, USP/NF
Formsolid

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