D-Glutamic acid, >=99% (TLC)
Application
D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.
Biochem/physiol Actions
Unnatural isomer of glutamic acid.
General description
D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.
Packaging
1, 5, 25, 100 g in poly bottle
| Colour | white to off-white |
|---|---|
| Quality Level | 200 |
| mp | 200-202 °C (subl.) (lit.) |
| InChI key | WHUUTDBJXJRKMK-GSVOUGTGSA-N |
| InChI | 1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1 |
| Manufacturer | SIGMA-ALDRICH |
| Form | powder |
| Assay | ≥99% (TLC) |
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