Cholecalciferol, meets USP testing specifications
Application
Cholecalciferol has been used:to induce arterial medial calcification (AMC) in miceto study its impact in vascular remodeling associated with vascular calcification (VC) in murine model of obesity and insulin resistance (ob/ob mice)to study its effect on anchorage dependent growth of RWPE2-W99 cells in monolayer culture
Biochem/physiol Actions
Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
General description
Cholecalciferol (vitamin D3), a fat-soluble steroid is produced in the skin.
Packaging
250 mg in ampule
1 g in ampule
25 g in glass bottle
| Colour | white |
|---|---|
| InChI key | QYSXJUFSXHHAJI-YRZJJWOYSA-N |
| InChI | 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/ |
| Manufacturer | SIGMA-ALDRICH |
| Agency | meets USP testing specifications, USP/NF |
| Form | crystalline |
| Assay | 97.0-103.0% |
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