Brain Natriuretic Peptide-32 human, >=97% (HPLC), powder

Brain Natriuretic Peptide-32 human, >=97% (HPLC), powder

Stock Code: 3589730
Manufacturer Part No: B5900-.5MG
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Amino Acid Sequence

Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His

Application

Brain natriuretic peptide-32 (BNP-32) has been used to culture skeletal muscle cells.

Biochem/physiol Actions

Brain natriuretic peptide (type B natriuretic peptide) was originally isolated from brain, but is mainly produced in myoendocrine cells of the heart ventricles from which it is released into the circulation. It is involved in blood pressure control and cardiovascular homeostasis.

General description

The gene encoding brain natriuretic peptide-32 (BNP-32) is localized on human chromosome 1p36.22. It is implicated in several biological functions such as diuresis, natriuresis, hypotensive action and inhibition of aldosterone secretion. BNP-32 acts as a potential biomarker of high left ventricular-diastolic pressure in patients with symptomatic left ventricular (LV) dysfunction. Elevated expression of this protein is observed in acute myocardial infarction (AMI) patients.

Quality Level200
InChI keyHPNRHPKXQZSDFX-OAQDCNSJSA-N
InChI1S/C143H244N50O42S4/c1-13-76(10)112-137(232)189-99(68-199)131(226)188-98(67-198)130(225)187-97(66-197)129(224)186-96(65-196)117(212)166-59-105(202)169-90(52-72
ManufacturerSIGMA-ALDRICH
CompositionPeptide content, ≥65%
Formpowder
Assay≥97% (HPLC)

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