BQ-123, >=99%, lyophilized powder

Stock Code: 3573273
Manufacturer Part No: B150-1MG
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Amino Acid Sequence

cyclo-Asp-Pro-Val-Leu-Trp

Application

BQ-123 has been used as a selective endothelin-A receptor antagonist to study its effects on tumor necrosis factor ? (TNF?)-induced human airway smooth muscle cells (HASMCs) proliferation. It is also used as endothelin-A receptor antagonist to study its effects on TNF?-induced granulocyte–macrophage colony-stimulating factor (GM-CSF) expression.

Biochem/physiol Actions

BQ-123 is an endothelin(Et) receptor antagonist and is exquisite for endothelin A (ETA) receptor. It is a cyclic pentapeptide.

Selective ETA endothelin receptor antagonist.

Quality Level200
InChI keyVYCMAAOURFJIHD-PJNXIOHISA-N
InChI1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formlyophilized powder
Assay≥99%

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