apo-Transferrin human, powder, >=98% (agarose gel electrophoresis)

Stock Code: 3593768
Manufacturer Part No: T4382-100MG
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£329.79 (exc VAT) per 100MG
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Application


Apo-Transferrin human has been used:to determine the competitive binding of bismuth to albumin and transferrin by fast performance liquid chromatography (FPLC)to study titanium-transferrin complex by electrochemical methodin the preparation of transferrin solution and in the formation of conjugates with ruthenium-complexes for cellular viability studies


Biochem/physiol Actions


Apo-transferrin is required for the survival and differentiation of oligodendroglial cells.


Apo-transferrin is an iron transport protein. The concentration of transferrin in blood plasma is about 35 ?M. Transferrin also functions in the transport of therapeutic, diagnostic and toxic ions like Ga3+, Ru3+ and Al3+. Polymorphism in TF gene has pathological implications in Parkinson?s disease.


General description


Apo-transferrin human is a glycoprotein, possessing homologous carboxyl and amino domain. Both the domain binds to one molecule of iron. Only 30% of transferrin is saturated with iron in the amino domain. Apo-transferrin in human is encoded by the gene TF which is localized on human chromosome 3q22.1.


Linkage


Similar to T 2252


Other Notes


Non-heme iron-transport protein.


Packaging


1 g in glass bottle


100, 500 mg in glass bottle

Quality Level200
ManufacturerSIGMA-ALDRICH
ImpuritiesHIV and HBsAg, source material tested negative
Formpowder
Assay≥98% (agarose gel electrophoresis)

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