alpha-Crystallin from bovine eye lens, lyophilized powder
Application
α-Crystallin is a lens protein that contains two homologous subunits: αA- and αB-crystallins. α-Crystallin displays chaperone-like activity and plays an important role in maintaining lens transparency. It has been noted that in diabetic conditions of rats there is a decline in the chaperone activity of α-Crystallin. Research has shown that a dietary antioxidant, curcumin, can prevent this loss of chaperone activity.
Biochem/physiol Actions
α-Crystallin is a small heat-shock protein that has chaperone-like activity, preventing protein aggregation in vitro. Point mutations in α-crystallin genes are believed to be responsible for hereditary cataract development.
Packaging
5 mg in glass bottle
25 mg in poly bottle
| Quality Level | 200 |
|---|---|
| Manufacturer | SIGMA-ALDRICH |
| Technique(s) | cell culture - mammalian: suitable |
| Storage Temp. | −20°C |
| Form | lyophilized powder |
| Assay | ≥70% (biuret) |
There are no downloads for this product.
