alpha-Casein from bovine milk, alphas-casein basis (electrophoresis), >=70% alphas-casein basis (ele

Stock Code: 3589951
Manufacturer Part No: C6780-1G
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£305.04 (exc VAT) per 1G
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Application

α-Casein from bovine milk is an Immunoglobulin E (IgE)-binding epitope belonging to the Casein phosphoprotein family. It has been used in studies of children with insulin-dependent diabetes mellitus (IDDM), due to the strong cross-reactivity of α-casein antibodies with insulin. Studies of children displaying (IDDM) show higher levels of α-casein antibodies than control siblings, which may serve as a risk marker for IDDM.

Biochem/physiol Actions

α-Casein can be an immunogen in young children, and anti-a-casein antibodies have strong cross-reactivity with insulin. This effect can explain the uncommon insulin autoimmunity, but it does not appear to progress to Type I diabetes.

Packaging

1, 5 g in poly bottle

250 mg in poly bottle

Preparation Note

Chromatographically purified

Quality Level200
ManufacturerSIGMA-ALDRICH
Technique(s)mass spectrometry (MS): suitable
Storage Temp.−20°C
Formlyophilized powder
Assay≥70% αs-casein basis (electrophoresis)

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