4-Chloro-DL-phenylalanine,

4-Chloro-DL-phenylalanine,

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Application

4-Chloro-DL-phenylalanine has been used:as tryptophan hydroxylase 1 (TPH1) inhibitor to treat kras+ male zebrafishto induce insomnia in rat modelsused to treat embryos to examine its effect on serotoninfor the selection of Enterococcus faecalis transformants with pESentA32 plasmidto feed flies to explore serotonin effect

Biochem/physiol Actions

Tryptophan hydroxylase inhibitor.

4-Chloro-DL-phenylalanine (PCPA) is an inhibitor of 5-hydroxytrytamine (5-HT) synthesis. It helps to improve the inflammation of lung tissue and remodeling pulmonary artery. PCPA can reduce the expression of tryptophan hydroxylase 1 (TPH1), matrix metalloproteinase (MMP) and pro-inflammatory factors.

Packaging

5, 25 g in poly bottle

Quality Level100
mp>240 °C (dec.) (lit.)
InChI keyNIGWMJHCCYYCSF-UHFFFAOYSA-N
InChI1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
ManufacturerSIGMA-ALDRICH
Formsolid

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