[Arg8]-Vasopressin acetate salt, >=95% (HPLC)

Stock Code: 3593862
Manufacturer Part No: V9879-25MG
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Amino Acid Sequence


Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]


Application


[Arg8]-Vasopressin acetate salt has been:used as a vasopressin receptor agonist to test vasopressin receptorsused to evoke peripheral V1a receptor-mediated vasoconstrictionas a supplement in Ham?s F12/Dulbecco?s modified Eagle?s medium for proximal tubule and glomerular explant cell culture


Biochem/physiol Actions


Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg8-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).


General description


Arginine vasopressin is a nonapeptide. It is produced by anterior hypothalamus nerve cells.


Other Notes


Lyophilized from 0.5% acetic acid


Preparation Note


[Arg8]-Vasopressin acetate salt dissolves water at 20 mg/ml to yield a clear colorless to faint yellow solution.

Quality Level200
InChI keyZHFGXNMADRRGQP-HPILINOVSA-N
InChI1S/C46H65N15O12S2.C2H4O2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥95% (HPLC)

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