![[Gly22]-Amyloid beta 1-40 Arctic human, >=95% (HPLC)](/images/1000x1000/3592283.jpg "[Gly22]-Amyloid beta 1-40 Arctic human, >=95% (HPLC)")
[Gly22]-Amyloid beta 1-40 Arctic human, >=95% (HPLC)
Amino Acid Sequence
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gly-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
General description
β-Amyloid peptides are the major constituents of senile plaques and neurofibrillary tangles that occur in the hippocampus, neocortex, and amygdala of patients with Alzheimer′s disease. Aβ (1-40) whether soluble or insoluble differentiates AD vs high pathology controls. The Arctic mutation E22G causes early onset of Alzheimer′s compared to wild type and promotes protofibril formation and neurotoxicity.
| Manufacturer | SIGMA-ALDRICH |
|---|---|
| Composition | Peptide Content, ≥75% |
| Storage Temp. | −20°C |
| Form | lyophilized |
| Assay | ≥95% (HPLC) |
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![[Gly22]-Amyloid beta 1-40 Arctic human, >=95% (HPLC)](/images/150x150/3592283.jpg "[Gly22]-Amyloid beta 1-40 Arctic human, >=95% (HPLC)")
