[Glu1]-Fibrinopeptide B human, >=90% (HPLC)

[Glu1]-Fibrinopeptide B human, >=90% (HPLC)

Stock Code: 3591192
Manufacturer Part No: F3261-.1MG
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Amino Acid Sequence

Glu-Gly-Val-Asn-Asp-Asn-Glu-Glu-Gly-Phe-Phe-Ser-Ala-Arg

Application

[Glu1]-Fibrinopeptide B human has been used:during LC-MS to avoid cross-contamination and to analyze the performance of mass spectrometer and LC-instrumentfor two-point calibration during 2D (dimensional) gel electrophoresis and protein identification by mass spectrometry of histidine (his)-Pup (prokaryotic ubiquitin-like protein) isolated from Mycobacterium smegmatisfor two-point calibration during one-dimensional gel electrophoresis and tandem mass spectrometry (MS) for the characterization of soluble protein sample obtained from the salivary gland homogenates of Cimex lectulariusas a standard for the correction of mass drift in data obtained from MS and MS/MS performed on peptides obtained from trypsin-digestion of protein disulfide isomerase (PDI)

Biochem/physiol Actions

Fibrin formation is an essential part in wound healing and inflammation. Fibrinopeptide B (FPB) can also cause chemotactic migration of neutrophils, without the simultaneous release of lysosome enzymes. It is produced during the coagulation of fibrinogen, which is essential for physiological homeostasis. It is involved in various disorders such as thrombosis and disseminated intravascular coagulation.

General description

Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer. It is cleaved off from the N-terminal of the fibrinogen ? chain. This peptide is composed of 14 amino acids.

Other Notes

Lyophilized from 0.1% TFA in H2O

Quality Level200
InChI keyKPBJTGOVJLITON-OECXYHNASA-N
InChI1S/C66H95N19O26/c1-31(2)53(85-48(90)29-73-55(100)35(67)16-19-49(91)92)64(109)83-42(26-46(69)88)61(106)82-43(27-52(97)98)62(107)81-41(25-45(68)87)60(105)78-37(1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥90% (HPLC)

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