N-(3-Dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride, commercial grade, powder
Application
N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide hydrochloride has been used for the formation of FND (fluorescent nanodiamonds)-transferrin bioconjugates.It has been used for crosslinking polyethylenimine to gold particles.It has been used as a carbodiimide linkage agent for coating of carboxylated polystyrene beads with biotinylated BSA (bovine serum albumin).
Biochem/physiol Actions
Water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. In addition, it will react with phosphate groups. EDAC has been used in peptide synthesis; crosslinking proteins to nucleic acids; and preparation of immunoconjugates as examples. Typically, EDAC is utilized in the pH range 4.0-6.0 without buffers. In particular, amine and carboxylate buffers should be avoided.
Packaging
1, 5 kg in poly drum
1, 5, 10, 25, 100 g in poly bottle
100 mg in poly bottle
| Quality Level | 300 |
|---|---|
| mp | 110-115 °C (lit.) |
| InChI key | FPQQSJJWHUJYPU-UHFFFAOYSA-N |
| InChI | 1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | H2O: ≤100 mg/mL |
| Form | powder |
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