(Tyr[SO3H]27)Cholecystokinin fragment 26-33 Amide, >=97% (HPLC), powder
Amino Acid Sequence
Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
Application
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 amide has been used to test its effects:to study its effects on ?5i/LMP7 immunoproteasome subunit in pancreatitison gastric emptying,food intake and c-Fos immunoreactivity in small litter (SL) and normal litter (NL) ratson the intestine and gallbladder motility in fish Ballan Wrasse
Biochem/physiol Actions
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 amide activates the cholecystokinin type B receptor and may mediate the blockage of opioid analgesia. It elicits anti-inflammatory effects. It mediates the inhibition on cytokine release, lymphocytes, and macrophages.
Neurotransmitter; predominant form of CCK in CNS and gastrointestinal tract; may play a role in satiety.
General description
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 amide is a sulfated cholecystokinin(CCK) octapeptide derived from the proCCK. It is present in plasma and endocrine cells.
Other Notes
C-Terminal octapeptide of cholecystokinin
| Quality Level | 200 |
|---|---|
| InChI key | IZTQOLKUZKXIRV-IVVJSLGPSA-N |
| InChI | 1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10 |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Form | powder |
| Assay | ≥97% (HPLC) |
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