[Val5]-Angiotensin II acetate salt hydrate, >=95% (HPLC), powder
Amino Acid Sequence
Asp-Arg-Val-Tyr-Val-His-Pro-Phe
Application
[Val5]-Angiotensin II acetate salt hydrate has been used to induce:renal damage in mice to study the role of human liver-type fatty acid-binding protein (hL-FABP)vascular inflammation in mice to study the interaction of cytosolic copper chaperone antioxidant-1 (Atox1) with tumor necrosis factor (TNF)-receptor-associated factor 4 (TRAF4)abdominal aortic aneurysm (AAA) in mice to study the role of vascular ATPase copper transporting ? (ATP7?)
Biochem/physiol Actions
[Val5]-Angiotensin II acts as an agonist for the angiotensin II type 1 receptor (AT1 receptor).
General description
[Val5]-Angiotensin II ([Val5]-ANG II) is an ANG II analog containing valine as the fifth amino acid in place of isoleucine in an ANG II octapeptide.
| Quality Level | 200 |
|---|---|
| InChI key | INQPQDZJLFYCRH-AXOAQIBVSA-N |
| InChI | 1S/C49H69N13O12.C2H4O2.H2O/c1-26(2)39(60-42(67)33(12-8-18-54-49(51)52)56-41(66)32(50)23-38(64)65)45(70)57-34(20-29-14-16-31(63)17-15-29)43(68)61-40(27(3)4)46(7 |
| Manufacturer | SIGMA-ALDRICH |
| Composition | acetate, 1.2-10.4% |
| Form | powder |
| Assay | ≥95% (HPLC) |
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