(+/-)-2-Amino-4-phosphonobutyric acid, solid

(+/-)-2-Amino-4-phosphonobutyric acid, solid

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Application

(±)-2-Amino-4-phosphonobutyric acid may be used as a glutamic acid receptor blocker in perfusion solution in the eye tissue electroretinography studies.

Biochem/physiol Actions

NMDA glutamate receptor antagonist.

Caution

Hygroscopic, store desiccated.

General description

(±)-2-Amino-4-phosphonobutyric acid or DL-AP4 is a group III nonselective metabotropic glutamate receptor (mGluR) agonist. L-2-amino-4-phosphonobutyric acid (L-Ap4) displays close to 500-fold selectivity for group III mGluRs.

Packaging

1 g in poly bottle

100, 250, 500 mg in poly bottle

Colourwhite
InChI keyDDOQBQRIEWHWBT-UHFFFAOYSA-N
InChI1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)
ManufacturerSIGMA-ALDRICH
Formsolid

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