Xanthine Oxidase from bovine milk, Grade IV, ammonium sulfate suspension, 0.1-0.4 units/mg protein

Stock Code: 3581544
Manufacturer Part No: X4875-40UN
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Analysis Note


Protein determined by biuret


Biochem/physiol Actions


Although xanthine oxidase is found widely distributed in multiple tissues, it is highly expressed in endothelial and epithelial cells. Its expression was also increased in infected tissues where it was shown to have an anti-microbial effect due to its ability to generate reactive oxygen species.


Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species.


General description


Formerly E.C. 1.1.3.22


Physical form


Suspension in 2.3 M (NH4)2SO4 containing 1 mM sodium salicylate


Unit Definition


One unit will convert 1.0 µmole of xanthine to uric acid per min at pH 7.5 at 25 °C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.

Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
Formammonium sulfate suspension

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