Uricase from Candida sp., recombinant, expressed in E. coli, lyophilized powder, >=2 units/mg solid

Biochem/physiol Actions

Suitable for the determination of uric acid in clinical analysis.

General description

Uricase deficient mice develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.

Packaging

250, 1000 units in glass bottle

Physical form

Powder; contains citrate and sucrose

Unit Definition

One unit will oxidize 1.0 µmole of uric acid to allantoin per minute at pH 8.5 at 25 °C.

Quality Level	200
InChI key	VPXDHZMLJOJKOX-UHFFFAOYSA-N
InChI	1S/C18H23N4O14P.H3N/c23-5-7-14(13(28)16(34-7)22-4-2-10(25)20-18(22)30)36-37(31,32)33-6-8-11(26)12(27)15(35-8)21-3-1-9(24)19-17(21)29;/h1-4,7-8,11-16,23,26-28H,
Manufacturer	SIGMA-ALDRICH
Storage Temp.	−20°C
Form	lyophilized powder