Pyrimidine nucleoside phosphorylase, recombinant, expressed in E. coli, >=1300 U/mL

Stock Code: 3578824
Manufacturer Part No: 39488-5ML
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Application


Pyrimidine nucleoside phosphorylase (PyNPase) may be used as a marker to predict the malignant potential of breast cancer, especially lymph node metastasis. PyNPase is used to study breast cancer, specifically its role in angiogenesis.


Biochem/physiol Actions


Pyrimidine nucleoside phosphorylase (PyNPase) is a glycosyltransferase that catalyzes the conversion of pyrimidine nucleoside and phosphate to a pyrimidine base and ?-D-ribose 1-phosphate. PyNPase plays a significant role in breast cancer angiogenesis.


Unit Definition


One unit will convert 1 µmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per minute at pH 7.4 and 25°C

Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formliquid

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