Monoamine Oxidase B human, ~2.5 mg per vial, recombinant, expressed in baculovirus infected BTI inse

Stock Code: 3579888
Manufacturer Part No: M7441-1VL
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Application


Monoamine Oxidase B has been used in a study to assess the effect of age in 23 different regions of the human brain. It has also been used in a study to determine the specific locations of monoamine oxidase in the human brain.


Drugs that inhibit monoamine oxidase B activity are used for the treatment of various neurological disorders including depression.


Biochem/physiol Actions


MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.


General description


Monoamine Oxidase B is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs.


Unit Definition


kynuramine deamination activity: One unit will deaminate 1 nanomole of kynuramine per minute at pH 7.4 at 37 deg C.

Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−70°C
Formliquid

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