beta-Glucuronidase from abalone entrails, Purified, aqueous solution, beta-glucuronidase >=100,000 u

Stock Code: 3581357
Manufacturer Part No: SRE0023-50ML
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Application


Technical Article Comparing Performance of Different EnzymesLearn more about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine.


Biochem/physiol Actions


?-Glucuronidase (GUSB) is a lysosomal enzyme, that degrades glucuronate-containing glycosaminoglycans. ?-glucuronidase, obtained from abalone has the ability to hydrolyze samples, that has high analyte concentrations. Absence of ?-glucuronidase results in mucopolysaccharidosis type VII (MPSVII), which leads to lysosomal storage in the brain.


Packaging


25, 50 mL in glass bottle


Physical form


Supplied as an aqueous solution containing L-proline, ammonium acetate and sodium azide


Unit Definition


One Sigma or modified Fishman unit will liberate 1.0 µg of phenolphthalein from phenolphthalein glucuronide per hr at 37 °C at pH 3.8 (30 min assay).

Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
Formaqueous solution

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