Adenosine Deaminase from bovine spleen, Type X, buffered aqueous glycerol solution, >=130 units/mg p

Adenosine Deaminase from bovine spleen, Type X, buffered aqueous glycerol solution, >=130 units/mg p

Stock Code: 3578971
Manufacturer Part No: A5043-250UN
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Analysis Note


Protein determined by biuret.


Application


Adenosine Deaminase from bovine spleen has been used in the immobilization on biostrip for stability and catalytic studies.


Adenosine deaminase is useful in various molecular biology assays, such as glycerol release assays . Adenosine deaminase is a potential target for treatments of combined immunodeficiency disease.


Biochem/physiol Actions


Adenosine deaminase is a purine catabolic enzyme which catalyzes the deamination of adenosine and 2′-deoxyadenosine with approximately equal specificity. It is ubiquitous in mammalian tissue, and deficiency in adenosine deaminase has been associated with severe combined immunodeficiency disease.


General description


Molecular weight: 32.5-33 kDapI: 4.85


Physical form


Solution in 50% glycerol, 5 mM potassium phosphate, pH 6.0


Unit Definition


One unit will deaminate 1.0 µmole of adenosine to inosine per min at pH 7.5 at 25 °C.

Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
Formbuffered aqueous glycerol solution

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