S-(-)-Carbidopa, >=98% (TLC), powder

Stock Code: 3577671
Manufacturer Part No: C1335-100MG

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Descriptions

Biochem/physiol Actions

Peripheral inhibitor of L-aromatic amino acid decarboxylase. When co-administered with L-DOPA, it prevents extra-CNS conversion to dopamine, thereby increasing CNS concentrations of effective compounds. Selectively cytotoxic to human pulmonary carcinoid and small cell lung carcinoma cells by increasing H₂O₂ in these cell lines, which are sensitive to reactive oxygen species.

General description

Carbidopa is used for treating restless legs (RL) syndrome and periodic leg movements in sleep (PLMS). Carbidopa along with levodopa is used to treat Parkinson?s disease.

Packaging

100 mg in glass bottle

25 mg in poly bottle

Specifications

Quality Level	200
InChI key	TZFNLOMSOLWIDK-JTQLQIEISA-N
InChI	1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/m0/s1
Manufacturer	SIGMA-ALDRICH
Solubility	methanol and 1 drop HCl: 4.90-5.10 mg/mL, clear, colorless to faintly yellow
Form	powder
Assay	≥98% (TLC)