2(3)-O-(4-Benzoylbenzoyl)adenosine 5-triphosphate triethylammonium salt, >=93%
Application
2?(3?)-O-(4-Benzoylbenzoyl)adenosine 5?-triphosphate triethylammonium salt has been used as a P2X4 receptor agonist in rat kidney sections, type I diabetes induced rats and astrocyte?neuron coculture. It has also been used as a synthetic ATP analog in isotonic E3 medium.
Useful as a photoaffinity label for proteins and enzymes that bind ATP.
Biochem/physiol Actions
2?(3?)-O-(4-Benzoylbenzoyl)adenosine 5?-triphosphate triethylammonium salt is a selective purinergic receptor (P2X) agonist. It is more potent than ATP at homodimeric P2X7 receptors. It also effectively activates P2X1, P2X2, and P2X3 receptors. Useful as a photoaffinity label for proteins and enzymes that bind ATP.
Selective P2X purinergic agonist. It is more potent than ATP at homodimeric P2X7 receptors.
General description
2?(3?)-O-(4-Benzoylbenzoyl)adenosine 5?-triphosphate is a photoreactive analog of ATP.
Other Notes
Mixed isomers
Packaging
5, 25 mg in glass bottle
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