3-Aminopropionitrile fumarate salt, metabolite

Descriptions

Application

3-Aminopropionitrile fumarate salt has been used as a lysyl oxidase (LOX) inhibitor:to inhibit collagen cross-linking during microtissue formation and culturein LIM domain only 1 (LMO1)- or vector-expressing BE2C neuroblastoma cell line in transwell migration and invasion assayin lysyl oxidase (LOX) activity assayto study requirement of LOX activity for inducing hypoxia-inducible factor (HIF)2A-dependent stiffness in mouse organoids

Biochem/physiol Actions

3-Aminopropionitrile (?-Aminopropionitrile (BAPN)) functions as an irreversible inhibitor of lysyl oxidase (LOX), an enzyme involved in collagen cross-linking.

In mammals, metabolism of 3-aminopropionitrile leads to release of cyanide ions. Metabolic activity is localized in the microsomal fraction of the liver, and is believed to proceed through a free-radical pathway.

Packaging

5, 10, 25 g in poly bottle

Specifications

No detailed specifications are available for this product.

Downloads

There are no downloads for this product.

Code	Description	Quality Level	mp	InChI key	InChI	Manufacturer	Form	Assay	Price
3577604	3-Aminopropionitrile fumarate salt, metabolite	200	177 °C (dec.) (lit.)	NYMXYZMHOZAPHQ-SEPHDYHBSA-N	1S/C4H4O4.2C3H6N2/c5-3(6)1-2-4(7)8;24-2-1-3-5/h1-2H,(H,5,6)(H,7,8);21-2,4H2/b2-1+;;	SIGMA-ALDRICH	powder	≥98% (TLC)	You need to be logged in to see prices.
3577605	3-Aminopropionitrile fumarate salt, metabolite	200	177 °C (dec.) (lit.)	NYMXYZMHOZAPHQ-SEPHDYHBSA-N	1S/C4H4O4.2C3H6N2/c5-3(6)1-2-4(7)8;24-2-1-3-5/h1-2H,(H,5,6)(H,7,8);21-2,4H2/b2-1+;;	SIGMA-ALDRICH	powder	≥98% (TLC)	You need to be logged in to see prices.
3577606	3-Aminopropionitrile fumarate salt, metabolite	200	177 °C (dec.) (lit.)	NYMXYZMHOZAPHQ-SEPHDYHBSA-N	1S/C4H4O4.2C3H6N2/c5-3(6)1-2-4(7)8;24-2-1-3-5/h1-2H,(H,5,6)(H,7,8);21-2,4H2/b2-1+;;	SIGMA-ALDRICH	powder	≥98% (TLC)	You need to be logged in to see prices.