Filipin III from Streptomyces filipinensis, >=85% (HPLC)

Filipin III from Streptomyces filipinensis, >=85% (HPLC)

Application

Filipin has been used in a double staining procedure as a probe for the detection of lipoproteins in polyacrylamide gel and immobilized on nitrocellulose membranes. It is also widely used to localize and quantitate unesterified cholesterol by virtue of a specific fluorescent complex.

Biochem/physiol Actions

Filipin is a polyene macrolide antibiotic and antifungal. The antifungal mechanism of action may be due to altering membrane permeability and associated functions by binding to membrane sterols. Filipin inhibits prion protein (PrP) endocytosis and causes the release of PrP from the plasma membrane.

Other Notes

Filipin III is the major component of 8 isomeric components in filipin.

Packaging

1, 5 mg in glass bottle

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Code Description Quality Level mp InChI key InChI Manufacturer Form Assay Price Quantity
3577780 Filipin III from Streptomyces filipinensis, >=85% (HPLC) 300 163-180 °C IMQSIXYSKPIGPD-BWJOQPJXSA-N 1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,2 SIGMA-ALDRICH powder ≥85% (HPLC)
£232.61 (exc VAT) per 1MG
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3577781 Filipin III from Streptomyces filipinensis, >=85% (HPLC) 300 163-180 °C IMQSIXYSKPIGPD-BWJOQPJXSA-N 1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,2 SIGMA-ALDRICH powder ≥85% (HPLC)
£1,165.82 (exc VAT) per 5MG
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