Methotrexate hydrate, >=98% (HPLC), powder

Methotrexate hydrate, >=98% (HPLC), powder

Application

Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.

Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.

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Code Description Colour mp InChI key InChI Manufacturer Form Assay Price
3577618 Methotrexate hydrate, >=98% (HPLC), powder , yellow to very dark yellow to very dark orange 185-204 °C FPJYMUQSRFJSEW-ZOWNYOTGSA-N 1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30 SIGMA-ALDRICH powder ≥98% (HPLC)
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3577619 Methotrexate hydrate, >=98% (HPLC), powder , yellow to very dark yellow to very dark orange 185-204 °C FPJYMUQSRFJSEW-ZOWNYOTGSA-N 1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30 SIGMA-ALDRICH powder ≥98% (HPLC)
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3577620 Methotrexate hydrate, >=98% (HPLC), powder , yellow to very dark yellow to very dark orange 185-204 °C FPJYMUQSRFJSEW-ZOWNYOTGSA-N 1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30 SIGMA-ALDRICH powder ≥98% (HPLC)
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3577621 Methotrexate hydrate, >=98% (HPLC), powder , yellow to very dark yellow to very dark orange 185-204 °C FPJYMUQSRFJSEW-ZOWNYOTGSA-N 1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30 SIGMA-ALDRICH powder ≥98% (HPLC)
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3577622 Methotrexate hydrate, >=98% (HPLC), powder , yellow to very dark yellow to very dark orange 185-204 °C FPJYMUQSRFJSEW-ZOWNYOTGSA-N 1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30 SIGMA-ALDRICH powder ≥98% (HPLC)
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