Sodium iodoacetate, >=98%

Application

Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.

Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Biochem/physiol Actions

Used to induce osteoarthritis-like lesions and functional impairment in rats, for testing of chondroprotective agents and diagnostic imaging techniques.

Packaging

25, 100 g in glass bottle

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Code Description Quality Level mp InChI key InChI Manufacturer Form Assay Price Quantity
3577807 Sodium iodoacetate, >=98% 200 208 °C (dec.) (lit.) AGDSCTQQXMDDCV-UHFFFAOYSA-M 1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1 SIGMA-ALDRICH powder ≥98%
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3577808 Sodium iodoacetate, >=98% 200 208 °C (dec.) (lit.) AGDSCTQQXMDDCV-UHFFFAOYSA-M 1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1 SIGMA-ALDRICH powder ≥98%
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