Protamine from salmon, Grade IV, Histone, free (Millon test)

Protamine from salmon, Grade IV, Histone, free (Millon test)

Stock Code: 3577871
Manufacturer Part No: P4005-1G
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£390.00 (exc VAT) per 1G
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Application


Protamine from salmon has been used to avoid in vitro AT complex formation in samples from dogs pre-treated with heparin. It has also been used to study the influences of external potential on adsorption of various proteins to a metal surface.


Biochem/physiol Actions


Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.


Protamines are found to displace histones in DNA during spermatogenesis in animals and plants. Protamine is useful as a heparin neutralizer during heart surgery, dialysis and in many other clinical procedures.


General description


Protamines are proteins rich in cysteine and arginine. It possesses many phosphorylation sites. Salmon fish contains around 15 genes encoding protamine. It is found to be localized to the sperm head.


Packaging


1, 5 g in poly bottle


250 mg in poly bottle

Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
ImpuritiesHistone, free (Millon test)
SolubilityH2O: soluble, clear to slightly hazy, colorless to faintly yellow
Formsolid

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