N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone, elastase inhibitor

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone, elastase inhibitor

Stock Code: 3577838
Manufacturer Part No: M0398-25MG
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£643.50 (exc VAT) per 25MG
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Application


N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone has been used as an elastase specific inhibitor.


Biochem/physiol Actions


Irreversible inhibitor of human leukocyte and neutrophil elastase.


N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).


General description


N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.

Quality Level200
mp159 °C
InChI keyPJGDFLJMBAYGGC-XLPNERPQSA-N
InChI1S/C22H35ClN4O7/c1-12(2)19(16(28)11-23)26-21(32)15-7-6-10-27(15)22(33)14(4)25-20(31)13(3)24-17(29)8-9-18(30)34-5/h12-15,19H,6-11H2,1-5H3,(H,24,29)(H,25,31)(H,2
ManufacturerSIGMA-ALDRICH
Solubilitymethanol: 50 mg/mL, clear, colorless
Formpowder
Assay≥98% (TLC)

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