Myricetin, >=96.0% (HPLC)
Application
Myricetin has been used:to study its preventive effect as an antioxidant on noise-induced hearing loss (NIHL) in ratsas a flavonoid compound to test antiviral activity of Bourbon virus (BRBV) and in inhibition of RNA-dependent RNA polymerase (RdRP)to study its effect as a treatment on biofilms of Streptococcus mutans and Candida albicansas a reference standard for the quantification of phenolic compounds from Juniperus species
Biochem/physiol Actions
Myricetin exerts anti-oxidant effects, and anti-inflammatory effects by regulating multiple signal pathways. It also displays anti-diabetic and hepatoprotective effects. Myricetin strongly inhibits yeast ?-glucosidase, glyoxalase I in vitro, and bovine milk xanthine oxidase. It also promotes complex formation between DNA and both topoisomerase I and II, an effect that may have implications in cancer chemotherapy. Myricetin also has various nutraceuticals values and therapeutic effects.
General description
Myricetin (MYR) is a natural polyhydroxyflavonol compound, first isolated from the bark of Morella rubra (Myrica rubra) tree.
| Quality Level | 200 |
|---|---|
| mp | >300 °C (lit.), ≥300 °C |
| InChI key | IKMDFBPHZNJCSN-UHFFFAOYSA-N |
| InChI | 1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H |
| Manufacturer | SIGMA-ALDRICH |
| Form | powder |
| Assay | ≥96.0% (HPLC) |
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