Methotrexate hydrate, >=98% (HPLC), powder

Stock Code: 3577618
Manufacturer Part No: A6770-100MG
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£195.00 (exc VAT) per 100MG
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Application


Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.


Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.

Colour, yellow to very dark yellow to very dark orange
mp185-204 °C
InChI keyFPJYMUQSRFJSEW-ZOWNYOTGSA-N
InChI1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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